Toxicity & Drug ADME
The most important pathways
QIAGEN provides a broad range of assay technologies for toxicology and pharmacology research, enabling analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation. The understanding of drug–body interactions is crucial to drug development. Drug absorption, distribution, metabolism, and excretion (ADME) is critical in all phases of drug development programs, providing key insights into how a drug will ultimately be treated or accepted by the body. In the late 1980s to the mid-1990s, 40% of all drug failures in clinical trials were due to unfavorable toxicology and ADME profiles. By developing and using new focused genomic tools, researchers are better prepared to test compounds to protect human health and the environment. Solutions optimized for these research studies are organized into more focused research topics, shown below.
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QIAGEN provides a broad range of assay technologies for amino acid metabolism research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for cancer drug target research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for cell death research that enable analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction...
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QIAGEN provides a broad range of assay technologies for DNA damage and repair research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for fatty acid metabolism research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for Huntington’s disease research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for lung cancer research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction...
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QIAGEN provides a broad range of assay technologies for MAP kinase signaling research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for mitochondria research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction...
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QIAGEN provides a broad range of assay technologies for neurotransmitter research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for NFkB signaling research that enable analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction...
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QIAGEN provides a broad range of assay technologies for Parkinson’s disease research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for PPAR signaling research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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QIAGEN provides a broad range of assay technologies for unfolded protein response research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal...
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