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App. Package, M48, Genetic Screening

For easy setup of protocols for genetic screening applications
  • Easy protocol setup with all protocols on one CD-ROM
  • Optimized protocols help to ensure reliable purification
  • Range of protocols increases processing flexibility

The App. Package, M48, Genetic Screening is a CD-ROM containing protocols for DNA purification from buccal cells (predigested with proteinase K) or blood cards (4 punches per purification) using the MagAttract DNA Mini M48 Kit on the BioRobot M48 workstation. These protocols provide operating commands for the workstation and allow easy setup through comprehensive, on-screen instructions.

Cat No./ID: 9016147
App. Package, M48, Genetic Screening
Software protocol package for genetic screening applications on the BioRobot M48 workstation
The App. Package, M48, Genetic Screening is intended for molecular biology applications. This product is not intended for the diagnosis, prevention, or treatment of a disease.
Performance

DNA yields depend on the sample type, number of nucleated cells in the sample, and the protocol used for isolation of DNA.

Principle

The BioRobot M48 and the MagAttract DNA Mini M48 Kit, with protocols on the App. Package, M48, Genetic Screening, reproducibly automate purification of genomic DNA. Purification of 6–48 samples per run is efficient and purified DNA performs well in downstream analyses.

The BioRobot M48 system provides fully automated purification of DNA using silica-coated magnetic particles, eliminating the need for tedious centrifugation steps. The easy-to-use workstation allows purification of 6–48 samples in a single run. Between processing runs, the worktable can be decontaminated using an integrated UV lamp to reduce the chances of environmental contamination.

Procedure

Protocols on the App. Package, M48, Genetic Screening, V1.1

Sample typeAmount Kit Nucleic acid
Buccal cells (predigested with proteinase K) 200 µl MagAttract DNA Mini M48 Kit DNA
Blood cards (4 punches each, pretreated in lysis buffer) 720 µl MagAttract DNA Mini M48 Kit DNA
Applications

The high-quality DNA obtained using the MagAttract DNA Mini M48 Kit with protocols in the App. Package, M48, Genetic Screening is suitable for use in many genetic screening applications, such as:

Genetic database construction and biobanking
Familial genetics, including prenatal and neonatal screening
Mutational analysis
Epidemiological studies

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