- Highly sensitive and accurate quantitative assay
- EAC standardized assay for reproducible results
- Compliance with EU IVD Directive 98/79/EC
- Easy workflow with ready-to-use solutions
The ipsogen PML-RARA bcr1 Kit is an in vitro molecular diagnostic kit for real-time PCR on the Rotor-Gene Q and other real-time PCR instruments. The kit provides reagents optimized for reliable and sensitive detection and quantification of PML-RARA bcr1 fusion transcripts, relative to ABL control gene expression, in total RNA from bone marrow or peripheral blood samples in a subgroup of acute myeloid leukemia (AML) patients diagnosed with M3 cytomorphology and t(15;17)(q22;q21) translocation, with a breakpoint into PML intron 6. The test is intended to be used as an aid to monitor efficacy of treatment in patients undergoing therapy, and for minimal residual disease (MRD) follow-up to monitor disease relapse.