Gene Pathways
Focusing on gene pathways and networks in neurodegenerative disease
Analysis of Alzheimer's disease pathways provides valuable information about risk factors for disease, factors affecting disease outcomes, and possible biomarkers or targets for therapy. While pathways involved in the initiation and progression of Alzheimer's disease are far from completely understood, genes involved in amyloid β protein generation, clearance, degradation, and signal transduction, as well as neuronal toxicity and inflammation, are strong candidates for further study.

QIAGEN offers complete solutions to simplify and streamline each step of your Alzheimer's disease pathway profiling experiments. Pathway- and disease-focused PCR arrays enable quick and easy identification of variations in expression of genes relevant to your research. At GeneGlobe, QIAGEN also offers a broad portfolio of pathway-specific products for a variety of neurodegenerative diseases such as Parkinson’s disease and Huntington's disease, as well as for neurological functions such as neurogenesis or synaptic plasticity.

For immediate stabilization of RNA in tissues
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For low- to medium-throughput sample disruption for molecular analysis
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For isolation and purification of intracellular RNA from blood stabilized in PAXgene Blood RNA Tubes
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For fixation and stabilization of human tissue specimens (max. 4 x 15 x 15 mm in size)
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For immediate stabilization of DNA, RNA, and protein in tissues
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For simultaneous purification of genomic DNA and total RNA, including miRNA, from cells and difficult-to-lyse tissue
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For purification of total RNA from all types of tissue using gDNA Eliminator Solution
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For purification of total RNA from formalin-fixed, paraffin-embedded tissue sections
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For purification of total RNA from tissues fixed and stabilized in PAXgene Tissue Containers
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For purification of microRNA and total RNA from tissues fixed and stabilized in PAXgene Tissue Containers
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For whole transcriptome amplification of total RNA or mRNA from single cells
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For parallel whole genome and whole transcriptome amplification from cells and limited samples
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For fully automated sample prep using QIAGEN spin-column kits
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For purification of miRNA and total RNA from whole blood
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For isolation and purification of intracellular RNA from blood stabilized in PAXgene Blood RNA Tubes
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For cDNA synthesis and genomic DNA elimination in RNA samples for use with RT2 Profiler PCR Arrays and RT2 lncRNA PCR Arrays
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For preamplification of cDNA from small or FFPE samples of RNA for analysis on RT2 Profiler PCR Arrays
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For outstanding performance in real-time PCR
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For pathway-focused gene expression analysis using laboratory-verified assays
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For modeling, analyzing, and understanding complex 'omics data
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