Key scientific publications

Browse and read publications by researchers and experts to stay up-to-date with scientific advances and breakthroughs in single cell research.
Single-cell genomics – methods and protocols

Hou, Y. et al. (2015) Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing. GigaScience 4:37

Korfhage, C. et al. (2015) Parallel WGA and WTA for Comparative Genome and Transcriptome NGS Analysis Using Tiny Cell Numbers. Curr Protoc Mol Biol. 2015 Jul 1
Korfhage, C. et al. (2015) Whole-Transcriptome Amplification of Single Cells for Next-Generation Sequencing. Curr Protoc Mol Biol. 2015 Jul 1

Cancer, neuroscience or stem cell research

Zhang, C.-Z. et al. (2015) Chromothripsis from DNA damage in micronuclei. Nature, published online 27 May 2015
Yao, X. et al. (2014) Tumor cells are dislodged into the pulmonary vein during lobectomy., J Thorac Cardiovasc Surg.148(6)
Wang, Y.. et al. (2014) Clonal evolution in breast cancer revealed by single nucleus genome sequencing, Nature 512
Hou, Y. et al. (2012) Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell 148, 873
Jeong, J.H. (2015) Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism, MOLECULAR METABOLISM 4
Lee, D. et al. (2015) Apelin-13 Enhances Arcuate POMC Neuron Activity via Inhibiting M-Current. PLoS ONE 10(3): e0119457.doi:10.1371/journal.pone.0119457

Aneuploidy and genome profiling in blastomere research

Wells, D. et al. (2015) Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation. J Med Genet. 2014 Aug;51(8)
Thornhill, A.R. et al. (2015) Karyomapping—a comprehensive means of simultaneous monogenic and cytogenetic PGD: comparison with standard approaches in real time for Marfan syndrome, Journal of Assisted Reproduction and Genetics, Volume 32
Xu, J. et al. (2015) Embryo Genome Profiling by Single-Cell Sequencing for Preimplantation Genetic Diagnosis in a β-Thalassemia Family Clinical Chemistry 61:4
Wang, L. et al. (2014) Detection of Chromosomal Aneuploidy in Human Pre-implantation Embryos by Next Generation Sequencing, Biology of Reproduction March 19,2014
Choi, Y.H. et al. (2015) Accuracy of preimplantation genetic diagnosis in equine in vivo-recovered and in vitro-produced blastocysts. Reprod Fertil Dev. 2015 Mar 17. doi: 10.1071/RD14419.

Microbiology, infectious disease research, metagenomics

Mansor, M. et al. (2015) Metabolic diversity and ecological niches of Achromatium populations revealed with single-cell genomic sequencing, Frontiers in Microbiology, Vol. 6
Nair, S. et al. (2014) Single-cell genomics for dissection of complex malaria infections, Genome Res. 2014. 24:1028-1038
Zoll, J. et al. (2015) Direct multiplexed whole genome sequencing of respiratory tract samples reveals full viral genomic information, Journal of Clinical Virology 66 (2015) 6–11
Lai Y., et al. (2015) Metagenomic Human Repiratory Air in a Hospital Environment. PLoS ONE 10(10): e0139044. doi:10.1371/journal.pone.0139044