Hematopoiesis
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Hematopoiesis is the process of blood cell proliferation and differentiation from multipotent hematopoietic stem cells (HSCs). HSCs are capable of self-renewal as well as differentiation into all mature blood cells. HSCs initially differentiate into lymphoid and myeloid progenitor cells. Lymphoid progenitors differentiate into natural killer cells and lymphocytes (B cells and T cells). Myeloid progenitors differentiate into 4 cell classes: erythrocytes, mast cells, megakaryocytes (which form platelets), and myeloblasts. Myeloblasts differentiate into basophils, neutrophils, eosinophils, and monocytes (which later mature into macrophages). Most blood cells develop and mature in the bone marrow, with the exception of T cells, which develop in the bone marrow and migrate to the thymus for final maturation. Hematopoietic cells play important roles in oxygen dispersal, hemostasis, and immunity. Hematopoietic dysregulation can result in an excess or a lack of certain blood cell types, leading to immune system disorders, cancer, various anemias, or coagulopathy. ...
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Hematopoiesis is the process of blood cell proliferation and differentiation from multipotent hematopoietic stem cells (HSCs). HSCs are capable of self-renewal as well as differentiation into all mature blood cells. HSCs initially differentiate into lymphoid and myeloid progenitor cells. Lymphoid progenitors differentiate into natural killer cells and lymphocytes (B cells and T cells). Myeloid progenitors differentiate into 4 cell classes: erythrocytes, mast cells, megakaryocytes (which form platelets), and myeloblasts. Myeloblasts differentiate into basophils, neutrophils, eosinophils, and monocytes (which later mature into macrophages). Most blood cells develop and mature in the bone marrow, with the exception of T cells, which develop in the bone marrow and migrate to the thymus for final maturation. Hematopoietic cells play important roles in oxygen dispersal, hemostasis, and immunity. Hematopoietic dysregulation can result in an excess or a lack of certain blood cell types, leading to immune system disorders, cancer, various anemias, or coagulopathy.

QIAGEN provides a broad range of assay technologies for hematopoiesis research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation. Solutions optimized for hematopoiesis studies include PCR array, miRNA, siRNA, mutation analysis, pathway reporter, chromatin IP, DNA methylation, and protein expression products.
  • Description
RT² Profiler PCR Array
The Human Hematopoiesis RT² Profiler PCR Array profiles the expression of 84 genes related to the development of blood-cell lineages from HSCs through progenitor stem cells. Blood cell...

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Species
Human
Cat. no.
PAHS-054Z
RT² Profiler PCR Array
The Mouse Hematopoiesis RT² Profiler PCR Array profiles the expression of 84 genes related to the development of blood-cell lineages from HSCs through progenitor stem cells. Blood cell...

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Species
Mouse
Cat. no.
PAMM-054Z
RT² Profiler PCR Array
The Rat Hematopoiesis RT² Profiler PCR Array profiles the expression of 84 genes related to the development of blood-cell lineages from HSCs through progenitor stem cells. Blood cell...

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Species
Rat
Cat. no.
PARN-054Z
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